July 11, 2002 -- It happened by accident: patients of plastic surgeons started reporting that shots to remove wrinkles were clearing up chronic headaches as well.

A total of 13 studies involving 650 patients were presented about Botox® (botulinum toxic A) at a recent American Headache Society's conference, showing evidence that shots of Botox® could help with migraine and tension headaches. Now, fans of the substance, who swear that it is the best wrinkle-reliever that money can buy, as well as the best anti-perspirant (it is supposed to stop excessive sweating) are now tooting its horn even more than before.

How does it work? Small amounts of botulinum toxin A are injected directly into muscle to cause paralysis leading to wrinkle relaxation, a feat that incited famed NY Times columnist Maureen Dowd to assert that it was creating a "generation of expressionless zombies." In April of 2002, Botox® was approved by the FDA for cosmetic use, causing hordes of people running to their local plastic surgeon.

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